Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.70 |
| ▸ | NOS3 | P29474 | 5/20 | 0.70 |
| ▸ | NOS1 | P29475 | 4/20 | 0.70 |
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14630870 | 0.98 | NOS2 (0.68) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL6938337 | 0.88 | NOS2 (0.66) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL729575 | 0.86 | NOS3 (0.63) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL27678823 | 0.85 | NOS3 (0.61) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL5744814 | 0.85 | NOS3 (0.61) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL3443609 | 0.85 | NOS3 (0.61) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL5746040 | 0.85 | NOS3 (0.61) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL5749578 | 0.85 | NOS3 (0.61) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL19309208 | 0.85 | NOS3 (0.61) | NOS2NOS3NOS1GABRPGABRD | |
| SCHEMBL8527159 | 0.85 | NOS3 (0.61) | NOS2NOS3NOS1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55072166-A | — | — | None | — | — | JP | disclosed |
| US-20260001885-A1 | 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS | MERCK SHARP & DOHME (NL) | 2026-01-01 | — | — | US | disclosed |
| US-20230331729-A1 | 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS | MERCK SHARP & DOHME (NL) | 2023-10-19 | — | — | US | disclosed |
| EP-4249076-A2 | (S)-4-(8-AMINO-3-(1-(BUT-2-YNOYL)PYRROLIDIN-2-YL)IMIDAZO[1,5-A]PYRAZIN-1-YL)-2-METHOXY-N-(PYRIDIN-2-YL)BENZAMIDE AS BTK-INHIBITOR | Merck Sharp & Dohme B.V. (NL) | 2023-09-27 | — | — | EP | disclosed |
| WO-2023137182-A1 | METHODS OF TREATING MYELOPROLIFERATIVE DISORDERS BASED ON BTK OCCUPANCY & RESYNTHESIS RATE | TELIOS PHARMA INC. (US) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023100501-A1 | ADHESIVE FOR SKIN AFFIXATION AND ADHESIVE TAPE FOR SKIN AFFIXATION | 東洋インキＳＣホールディングス株式会社 | 2023-06-08 | — | — | WO | disclosed |
| EP-3495368-B1 | (S)-4-(8-AMINO-3-(1-(BUT-2-YNOYL)PYRROLIDIN-2-YL)IMIDAZO[1,5-A]PYRAZIN-1-YL)-2-METHOXY-N-(PYRIDIN-2-YL)BENZAMIDE AS BTK-INHIBITOR | MERCK SHARP & DOHME (NL) | 2023-05-31 | — | — | EP | disclosed |
| WO-2022266285-A1 | TREATMENT OF SYMPTOMS ASSOCIATED WITH MYELOPROLIFERATIVE NEOPLASMS | TELIOS PHARMA INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| CN-107531683-B | USP7 inhibitor compounds and methods of use | 豪夫迈·罗氏有限公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3271333-B1 | USP7 INHIBITOR COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2022-01-12 | — | — | EP | disclosed |
| EP-0065817-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACIDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0035860-B1 | PROCESS FOR PRODUCING ETHYLIDENE DIACETATE AND/OR ACETALDEHYDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-03-14 | — | — | EP | disclosed |
| EP-0048174-B1 | PROCESS FOR PRODUCING VINYL ACETATE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-02-22 | — | — | EP | disclosed |
| EP-0065817-A1 | Process for producing carboxylic acids | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0055622-A1 | Process for producing acetic anhydride | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-07-07 | — | — | EP | disclosed |
| EP-0048174-A1 | Process for producing vinyl acetate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-03-24 | — | — | EP | disclosed |
| EP-0035860-A2 | Process for producing ethylidene diacetate and/or acetaldehyde | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1981-09-16 | — | — | EP | disclosed |
| JP-S5572166-A | PREPARATION OF 2,5-DIAMINO-4-PROPYLPYRIDINE | KOEI CHEM CO LTD | 1980-05-30 | — | — | JP | disclosed |
| US-4115397-A | 1,3,5,7-TETRA(2-PYRIDYLIMINO)-BENZODIPYRROLES | FORD MOTOR COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-3965100-A | 2,3-Dihydrocyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one and its derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001885-A1 | 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS | BTK, ABL1, FLT3 | NOS2 1824/4885NOS3 2190/4885NOS1 2141/4885 |
| US-20230331729-A1 | 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS | BTK, SYK, ABL1 | NOS2 2722/4885NOS3 2614/4885NOS1 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.