Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559267 | 0.87 | NOX1 (0.53) | GABRA1GABRB2GAAMAPTNOX1 | |
| SCHEMBL10561619 | 0.80 | LIPG (0.46) | MAPTMEN1ALOX15KMT2ACYP3A4 | |
| SCHEMBL25765754 | 0.71 | — | — | |
| SCHEMBL8723840 | 0.71 | GAA (0.41) | GAAMAPTNOX1MEN1ALOX15 | |
| SCHEMBL10537721 | 0.71 | — | — | |
| SCHEMBL10557429 | 0.71 | GABRA1 (0.41) | GABRA1GABRB2PDK2MAPTMEN1 | |
| SCHEMBL2582870 | 0.68 | NOX1 (0.53) | PDK2GAAMAPTNOX1MEN1 | |
| SCHEMBL12142036 | 0.68 | GABRA1 (0.48) | GABRA1GABRB2GAAMAPTNOX1 | |
| SCHEMBL2313040 | 0.67 | NOX1 (0.52) | GAAMAPTNOX1MEN1ALOX15 | |
| SCHEMBL2590797 | 0.67 | PDK2 (0.46) | GABRA1GABRB2PDK2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803269-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4707473-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-11-17 | — | — | US | disclosed |