Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GPR3 | P46089 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KIF11 | P52732 | 5/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL573588 | 0.84 | ALDH1A1 (0.70) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| Carbazole SCHEMBL29148121 | 0.84 | ALDH1A1 (0.70) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| Carbazole SCHEMBL28852407 | 0.84 | ALDH1A1 (0.78) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| SCHEMBL10582364 | 0.81 | CDK4 (0.56) | ALDH1A1GPR3HSD17B10KIF11GABRA1 | |
| Carbazole SCHEMBL28048441 | 0.81 | ALDH1A1 (0.82) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| Carbazole SCHEMBL28851970 | 0.79 | ALDH1A1 (0.70) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| Carbazole SCHEMBL29355407 | 0.78 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| Carbazole SCHEMBL30209164 | 0.78 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| Carbazole SCHEMBL30761795 | 0.78 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10KIF11AHR | |
| Carbazole SCHEMBL7650 | 0.78 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10KIF11AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873258-A | Benzo[c] carbazole propanediol containing anti tumor compositions and use | BURROUGHS WELLCOME CO. (US) | 1989-10-10 | — | — | US | disclosed |