Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Carbazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | GPR3 | P46089 | 1/20 | 0.70 |
| ▸ | KIF11 | P52732 | 5/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL28852407 | 0.90 | ALDH1A1 (0.78) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Carbazole SCHEMBL28213632 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Carbazole SCHEMBL7149138 | 0.87 | ALDH1A1 (0.74) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Carbazole SCHEMBL28048441 | 0.87 | ALDH1A1 (0.82) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Acridone SCHEMBL28404154 | 0.87 | ALDH1A1 (0.75) | ALDH1A1HSD17B10GPR3KDM4ESMN1; SMN2 | |
| Carbazole SCHEMBL28851970 | 0.85 | ALDH1A1 (0.70) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Carbazole SCHEMBL10565151 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Carbazole SCHEMBL30209164 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Carbazole SCHEMBL29627417 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GPR3KIF11AHR | |
| Carbazole SCHEMBL7650 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HSD17B10GPR3KIF11AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115372295-B | Method for efficiently detecting content of hyaluronic acid composition | 北京渼颜空间生物医药有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115372295-A | Method for efficiently detecting content of hyaluronic acid composition | 北京渼颜空间生物医药有限公司 | 2022-11-22 | — | — | CN | claimed |
| CN-112945946-B | Method for measuring hyaluronic acid gel in-vitro enzyme degradation rate | 青岛琛蓝海洋生物工程有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-114252436-A | Method for identifying natural fucosylated glycosaminoglycan | 牡丹江友搏药业有限责任公司 | 2022-03-29 | — | — | CN | claimed |
| CN-112945946-A | Method for measuring hyaluronic acid gel in-vitro enzyme degradation rate | 青岛琛蓝海洋生物工程有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-110423288-A | A kind of extraction of red heart potato slag pectin and identification method | UNIV TONGREN | 2019-11-08 | — | — | CN | claimed |
| CN-108776114-A | A kind of hyaluronic acid liposome ultraviolet fingerprint method measurement hyaluronic acid contents | 常州大学 | 2018-11-09 | — | — | CN | claimed |
| CN-108562574-A | Hyaluronic acid high throughput micro-scale rapid detection method | 常州大学 | 2018-09-21 | — | — | CN | claimed |
| CN-107602549-A | A kind of carbazolyl-containing Sai/oxadiazolyl Mannich bases and preparation method thereof | 陕西科技大学 | 2018-01-19 | — | — | CN | claimed |
| CN-106053369-A | Method for detecting content of free sodium hyaluronate in medical cross-linking sodium hyaluronate gel | 浙江景嘉医疗科技有限公司 | 2016-10-26 | — | — | CN | claimed |
| CN-104631131-A | Application of green complex enzyme in printing and dyeing pretreatment | QINGDAO XINYIFA INDUSTRY & TRADE CO LTD | 2015-05-20 | — | — | CN | claimed |
| JP-9306667-A | — | — | None | — | — | JP | disclosed |
| CN-122074575-A | Coffee fresh fruit micro-water peeling and degumming integrated processing method | — | 2026-05-26 | — | — | CN | disclosed |
| CN-121945178-A | Composite catalyst for preparing deuterated chloroform and preparation method thereof | 四川化工职业技术学院 | 2026-05-01 | — | — | CN | disclosed |
| US-12485154-B2 | Anti-influenza virus composition, composition for treating respiratory diseases, and anti-aging composition, comprising dark ginseng extract | CJ CHEILJEDANG CORPORATION (KR) | 2025-12-02 | — | — | US | disclosed |
| CN-1372547-A | Aminoalkoxy carbazoles for the treatment of CNS diseases | UPJOHN CO (US) | 2002-10-02 | — | — | CN | disclosed |
| EP-1210329-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017963-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |
| JP-H09306667-A | MANUFACTURE OF ORGANIC ELECTROLUMINESCENCE ELEMENT | SEIKO PRECISION KK | 1997-11-28 | — | — | JP | disclosed |
| US-5350633-A | Carbazole derivative desensitizer | SAKURA COLOR PRODUCTS CORPORATION (JP) | 1994-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12485154-B2 | Anti-influenza virus composition, composition for treating respiratory diseases, and anti-aging composition, comprising dark ginseng extract | GLA, MAVS, POLRMT | ALDH1A1 4461/4885HSD17B10 3230/4885GPR3 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.