Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567628 | 0.79 | SLC2A1 (0.39) | NCF1SLC2A1KDM4ELMNAMAPT | |
| SCHEMBL10567586 | 0.78 | NQO2 (0.41) | NCF1SLC2A1CYP2C19KDM4EMEN1 | |
| SCHEMBL10506904 | 0.78 | NCF1 (0.56) | NCF1SLC2A1CYP2C19KDM4EGAA | |
| SCHEMBL10840990 | 0.76 | SLC2A1 (0.58) | SLC2A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10507503 | 0.75 | CYP2C19 (0.52) | NCF1SLC2A1CYP2C19KDM4EPKM | |
| SCHEMBL10805500 | 0.74 | SLC2A1 (0.49) | SLC2A1CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL10507638 | 0.73 | SLC2A1 (0.47) | NCF1SLC2A1CYP2C19KDM4EPKM | |
| SCHEMBL10801118 | 0.71 | SLC2A1 (0.48) | NCF1SLC2A1CYP2C19LMNAMAPK1 | |
| SCHEMBL10568468 | 0.71 | SLC2A1 (0.41) | SLC2A1CYP2C19KDM4EGAAKMT2A | |
| SCHEMBL27368257 | 0.71 | LMNA (0.54) | PKMGAAKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818754-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1989-04-04 | — | — | US | claimed |
| US-4818754-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1989-04-04 | — | — | US | disclosed |
| EP-0243055-A2 | Pyrazolopyridine derivatives, process for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | disclosed |