Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467685 | 1.00 | POLB (0.38) | POLBHSP90AA1KMT2AMEN1TDP1 | |
| SCHEMBL9362514 | 0.81 | CYP19A1 (0.47) | POLBHSP90AA1KMT2AMEN1TDP1 | |
| SCHEMBL9362509 | 0.81 | CYP19A1 (0.47) | POLBHSP90AA1KMT2AMEN1TDP1 | |
| SCHEMBL9362865 | 0.78 | APP (0.43) | CYP3A4CYP2D6GRIK1GRIK2LMNA | |
| SCHEMBL9362870 | 0.78 | APP (0.43) | CYP3A4CYP2D6GRIK1GRIK2LMNA | |
| SCHEMBL10565622 | 0.76 | PDE2A (0.44) | POLBHSP90AA1KMT2AMEN1TDP1 | |
| SCHEMBL9362897 | 0.74 | CYP19A1 (0.43) | POLBHSP90AA1KMT2AMEN1TDP1 | |
| SCHEMBL6947959 | 0.74 | MEN1 (0.46) | POLBHSP90AA1KMT2AMEN1TDP1 | |
| SCHEMBL9082770 | 0.73 | POLB (0.40) | POLBHSP90AA1KMT2AMEN1TDP1 | |
| SCHEMBL9967727 | 0.71 | PDE2A (0.42) | CYP3A4CYP2D6GRIK1GRIK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266586-A | Fungicidal substituted triazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | claimed |