Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.47 |
| ▸ | RARG | P13631 | 15/20 | 0.47 |
| ▸ | RARA | P10276 | 14/20 | 0.47 |
| ▸ | RXRA | P19793 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.37 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566455 | 0.87 | RARA (0.50) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL10356134 | 0.82 | RARG (0.64) | RARBRARGRARARXRA | |
| SCHEMBL9187716 | 0.81 | RARG (0.56) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL27324962 | 0.80 | RARB (0.66) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL7564650 | 0.77 | PDK2 (0.45) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL8101908 | 0.76 | RARB (0.72) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL10566458 | 0.76 | RARG (0.47) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL20636868 | 0.73 | RARB (0.54) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL2910869 | 0.73 | RARB (0.59) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL20636826 | 0.73 | CYP3A4 (0.63) | RARBRARGRARARXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829080-A | SKIN DISORDERS, PSORIASIS, ACNE | L'OREAL (FR) | 1989-05-09 | — | — | US | disclosed |