Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815932 | 0.85 | SLC10A6 (0.47) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL30305428 | 0.85 | SLC10A6 (0.47) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL10569691 | 0.84 | CYP3A4 (0.41) | ALDH1A1MAPTCA1CA2TDP1 | |
| SCHEMBL5764011 | 0.80 | TDP1 (0.64) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL7291560 | 0.80 | CA12 (0.53) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL11464655 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL9522819 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL9620989 | 0.79 | TDP1 (0.57) | ALDH1A1CA1CA2TDP1L3MBTL1 | |
| SCHEMBL4427898 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL10571519 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTGAASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847294-A | Derivatives of 2-(substituted sulfamyl)-6-nitrobenzoic acids, useful as adjuncts to radiation therapy | MERCK & CO., INC. (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0265806-A1 | 2-(Substituted sulfamyl)-6-nitrobenzoic acids, amides and esters thereof useful as adjuncts to radiation therapy | MERCK & CO. INC. (US) | 1988-05-04 | — | — | EP | disclosed |
| US-4694020-A | Derivatives of 2-(substituted sulfamyl)-6-nitrobenzoic acids and pharmaceutical compositions | MERCK & CO., INC. (US) | 1987-09-15 | — | — | US | disclosed |