Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834852 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4108436 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4108437 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8902338 | 0.83 | MAOB (0.42) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8697832 | 0.83 | MEN1 (0.42) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27207986 | 0.83 | MAOB (0.42) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20235895 | 0.83 | MAOB (0.42) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8902340 | 0.83 | MAOB (0.42) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8126152 | 0.82 | MIF (0.52) | MEN1KMT2ASMN1; SMN2CA1CA2 | |
| SCHEMBL1962034 | 0.82 | MIF (0.52) | MEN1KMT2ASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829090-A | SECONDARY AMINES, ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-05-09 | — | — | US | disclosed |
| US-4803222-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4720587-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1988-01-19 | — | — | US | disclosed |
| US-4719046-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |