SCHEMBL1962034

SCHEMBL1962034

COC(=O)C(C)/N=C/c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MIF P14174 6/20 0.52
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
KMT2A Q03164 4/20 0.46
MEN1 O00255 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
FAAH O00519 1/20 0.41
PLA2G7 Q13093 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8259717 1.00 MIF (0.52) MIFCA1CA2KMT2AMEN1
SCHEMBL8126152 1.00 MIF (0.52) MIFCA1CA2KMT2AMEN1
SCHEMBL8125280 1.00 MIF (0.52) MIFCA1CA2KMT2AMEN1
SCHEMBL1962036 1.00 MIF (0.52) MIFCA1CA2KMT2AMEN1
SCHEMBL13201409 1.00 MIF (0.52) MIFCA1CA2KMT2AMEN1
SCHEMBL22832244 0.85 MIF (0.42) MIFCA1CA2KMT2AMEN1
SCHEMBL13696288 0.85 MIF (0.42) MIFCA1CA2KMT2AMEN1
SCHEMBL11128185 0.83 MIF (0.50) MIFCA1CA2KMT2AMEN1
SCHEMBL11128186 0.83 MIF (0.50) MIFCA1CA2KMT2AMEN1
SCHEMBL1959830 0.83 MEN1 (0.50) MIFKMT2AMEN1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62198700-A None JP disclosed
EP-4676917-A1 MODULATORS OF SORTILIN ACTIVITY Vesper Bio Aps (DK) 2026-01-14 EP disclosed
US-20250282749-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2025-09-11 US disclosed
EP-4469445-A1 COMPOUNDS AND METHODS OF USE Tango Therapeutics, Inc. (US) 2024-12-04 EP disclosed
WO-2024184468-A1 MODULATORS OF SORTILIN ACTIVITY VESPER BIO APS (DK) 2024-09-12 WO disclosed
EP-4428124-A1 MODULATORS OF SORTILIN ACTIVITY Vesper Bio Aps (DK) 2024-09-11 EP disclosed
WO-2023146991-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed
WO-2023146991-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. (US) 2023-08-03 WO disclosed
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION COCRYSTAL PHARMA, INC. 2023-05-25 US disclosed
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION COCRYSTAL PHARMA, INC. 2023-05-25 US disclosed
US-6878735-B2 Multi-substituted imidazolines and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-04-12 US disclosed
US-20050020586-A1 NF-kappaB inhibitors and uses thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-01-27 US disclosed
WO-2004066996-A1 NF-kB INHIBITORS AND USES THEREOF MICHIGAN STATE UNIVERSITY (US) 2004-08-12 WO disclosed
US-20030232870-A1 Multi-substituted imidazolines and method of use thereof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2003-12-18 US disclosed
US-20030232998-A1 NF-kB inhibitors and uses threreof BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2003-12-18 US disclosed
WO-2003101954-A2 NF-KB INHIBITORS AND USES THEREOF MICHIGAN STATE UNIVERSITY (US) 2003-12-11 WO disclosed
WO-2003101969-A1 MULTI-SUBSTITUDED IMIDAZOLINES AND METHOD OF USE THEREOF MICHIGAN STATE UNIVERSITY (US) 2003-12-11 WO disclosed
US-5331006-A Cholecystokinin, antisecretory agents WARNER-LAMBERT COMPANY (US) 1994-07-19 US disclosed
WO-1992004025-A1 AMINO ACID ANALOGS AS CCK ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1992-03-19 WO disclosed
JP-S62198700-A L-ASPARTYL-2-METHYL-O-(+), BETA-FENCHYLSERINE METHYL ESTER TAKASAGO CORP 1987-09-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159453-A1 INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION VIM, ACE, ACE2 MIF 32/4885CA1 2571/4885CA2 2050/4885
US-20030232998-A1 NF-kB inhibitors and uses threreof NFKBIA, IKBKB, IKBKG MIF 277/4885CA1 4167/4885CA2 3137/4885
US-20250282749-A1 COMPOUNDS AND METHODS OF USE CYP1B1, CYP2C19, UGT1A1 MIF 4575/4885CA1 1704/4885CA2 2825/4885
US-20050020586-A1 NF-kappaB inhibitors and uses thereof NFKBIA, IKBKB, IKBKG MIF 45/4885CA1 3192/4885CA2 3064/4885
US-20030232870-A1 Multi-substituted imidazolines and method of use thereof IKBKB, NFKBIA, IKBKG MIF 51/4885CA1 3588/4885CA2 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.