Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563558 | 0.82 | TDP2 (0.41) | AURKAAURKB | |
| SCHEMBL9835280 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL10568162 | 0.73 | — | — | |
| SCHEMBL9832273 | 0.69 | PDE4A (0.48) | — | |
| SCHEMBL10372616 | 0.68 | CHEK2 (0.48) | — | |
| SCHEMBL5618665 | 0.68 | EIF2AK2 (0.38) | AURKAAURKB | |
| SCHEMBL10568694 | 0.67 | AURKA (0.62) | AURKAAURKB | |
| SCHEMBL9830544 | 0.67 | PDE4A (0.51) | — | |
| SCHEMBL10567219 | 0.67 | TDP2 (0.39) | AURKAAURKB | |
| SCHEMBL10373859 | 0.67 | CHEK2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835280-A | Indoline compounds for synthesis of pharmaceutically active pyrrolobenzimidazoles | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-30 | — | — | US | disclosed |
| EP-0189103-A2 | Pyrrolo-benzimidazoles, process for their preparation, medicaments containing them and intermediates | Roche Diagnostics GmbH (DE) | 1986-07-30 | — | — | EP | disclosed |