Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951827 | 0.79 | NLRP3 (0.55) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL2951820 | 0.79 | NLRP3 (0.55) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL10571332 | 0.77 | NLRP3 (0.45) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL10567633 | 0.76 | NLRP3 (0.49) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL9856316 | 0.76 | NFKB1 (0.43) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL14634400 | 0.75 | NLRP3 (0.48) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL10573770 | 0.75 | NLRP3 (0.44) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL14634399 | 0.75 | NLRP3 (0.48) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL14634328 | 0.73 | KMT2A (0.44) | NLRP3NFKB1NFKB2RELA | |
| SCHEMBL14685942 | 0.73 | KMT2A (0.44) | NLRP3NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837345-A | CATALYTIC HYDROGENATION OF 2H-PYRAN-3(6H)-ONE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-06-06 | — | — | US | disclosed |