Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14942690 | 0.76 | HAVCR2 (0.56) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL11593915 | 0.75 | SMN1; SMN2 (0.62) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL1366538 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2ALOX15ALDH1A1MAPTPARP1 | |
| SCHEMBL24037002 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL18506623 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL18506621 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL13982464 | 0.72 | SMN1; SMN2 (0.45) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL14029138 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL1161921 | 0.72 | HDAC6 (0.47) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT | |
| SCHEMBL9878956 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2ALOX15TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814335-A | Antiviral compounds | BIOMEASURE, INCORPORATED (US) | 1989-03-21 | — | — | US | disclosed |
| US-4625026-A | 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities against herpes simplex virus type II infections | BIOMEASURE, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0123750-A1 | Condensed amino pyrimidinones and their use in the treatment and prophylaxis of viral infections | BIOMEASURE, INC. (US) | 1984-11-07 | — | — | EP | disclosed |