SCHEMBL10568266

SCHEMBL10568266

N#CC/C1=C\CCCCCCCCCC1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.40
CXCR3 P49682 2/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
ALOX15 P16050 2/20 0.38
USP2 O75604 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 3/20 0.37
NPC1 O15118 1/20 0.34
EPHX1 P07099 1/20 0.34
RAB9A P51151 1/20 0.34
PKM P14618 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28159058 1.00 CTSK (0.40) CTSKCXCR3SMN1; SMN2ALOX15USP2
SCHEMBL10779188 1.00 CTSK (0.40) CTSKCXCR3SMN1; SMN2ALOX15USP2
SCHEMBL9650250 1.00 CTSK (0.40) CTSKCXCR3SMN1; SMN2ALOX15USP2
SCHEMBL9650245 1.00 CTSK (0.40) CTSKCXCR3SMN1; SMN2ALOX15USP2
SCHEMBL10779184 1.00 CTSK (0.40) CTSKCXCR3SMN1; SMN2ALOX15USP2
SCHEMBL1003717 0.98
SCHEMBL1004654 0.91
Benzonitrile SCHEMBL8498100 0.82 TSHR (0.45) SMN1; SMN2ALOX15USP2NPSR1ALDH1A1
SCHEMBL14244155 0.79 SMN1; SMN2 (0.42) CTSKCXCR3SMN1; SMN2ALOX15USP2
SCHEMBL8521332 0.77 ALDH1A1 (0.43) CTSKSMN1; SMN2ALOX15USP2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4851552-A CYCLODODECANONE, CYANOACETIC ACID, HYDROLYSIS, CYCLIZATION, REDUCTION HUELS AKTIENGESELLSCHAFT (DE) 1989-07-25 US claimed
US-4755615-A Process for the production of cyclododecenylacetonitrile HUELS AKTIENGESELLSCHAFT (DE) 1988-07-05 US claimed
US-4722808-A Use of cyclododecenylacetonitrile as a fragrance component HUELS AKTIENGESELLSCHAFT (DE) 1988-02-02 US claimed
EP-0149054-B1 METHOD FOR THE PREPARATION OF CYCLODODECENYLACETONITRIL AND ITS USE AS FRAGRANCE OR AS A COMPONENT OF A FRAGRANT COMPOSITION HÜLS AKTIENGESELLSCHAFT (DE) 1987-02-04 EP claimed
US-4851552-A CYCLODODECANONE, CYANOACETIC ACID, HYDROLYSIS, CYCLIZATION, REDUCTION HUELS AKTIENGESELLSCHAFT (DE) 1989-07-25 US disclosed
US-4851552-A CYCLODODECANONE, CYANOACETIC ACID, HYDROLYSIS, CYCLIZATION, REDUCTION HUELS AKTIENGESELLSCHAFT (DE) 1989-07-25 US disclosed
US-4755615-A Process for the production of cyclododecenylacetonitrile HUELS AKTIENGESELLSCHAFT (DE) 1988-07-05 US disclosed
US-4755615-A Process for the production of cyclododecenylacetonitrile HUELS AKTIENGESELLSCHAFT (DE) 1988-07-05 US disclosed
US-4755615-A Process for the production of cyclododecenylacetonitrile HUELS AKTIENGESELLSCHAFT (DE) 1988-07-05 US disclosed
US-4722808-A Use of cyclododecenylacetonitrile as a fragrance component HUELS AKTIENGESELLSCHAFT (DE) 1988-02-02 US disclosed
US-4722808-A Use of cyclododecenylacetonitrile as a fragrance component HUELS AKTIENGESELLSCHAFT (DE) 1988-02-02 US disclosed
US-4722808-A Use of cyclododecenylacetonitrile as a fragrance component HUELS AKTIENGESELLSCHAFT (DE) 1988-02-02 US disclosed
EP-0149054-B1 METHOD FOR THE PREPARATION OF CYCLODODECENYLACETONITRIL AND ITS USE AS FRAGRANCE OR AS A COMPONENT OF A FRAGRANT COMPOSITION HÜLS AKTIENGESELLSCHAFT (DE) 1987-02-04 EP disclosed
EP-0149054-A2 Method for the preparation of cyclododecenylacetonitril and its use as fragrance or as a component of a fragrant composition HÜLS AKTIENGESELLSCHAFT (DE) 1985-07-24 EP disclosed