Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSE | P14091 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566700 | 0.84 | USP30 (0.37) | USP30USP2SMN1; SMN2ATMHRH3 | |
| SCHEMBL10563297 | 0.84 | USP30 (0.39) | USP30USP2SMN1; SMN2ATMHRH3 | |
| SCHEMBL10565341 | 0.83 | USP30 (0.43) | USP30USP2SMN1; SMN2ATMHRH3 | |
| SCHEMBL10564287 | 0.82 | GPR119 (0.39) | USP30USP2SMN1; SMN2MAPTHDAC1 | |
| SCHEMBL10568269 | 0.81 | CHRM2 (0.36) | USP2THRBTSHRHPGD | |
| SCHEMBL10565065 | 0.81 | MEN1 (0.45) | KDM4EMAPTTSHR | |
| SCHEMBL3498231 | 0.81 | HRH3 (0.41) | HRH3KDM4EMAPTTHRBCTSD | |
| SCHEMBL10701654 | 0.79 | CHRM2 (0.43) | USP30USP2SMN1; SMN2ATMHRH3 | |
| SCHEMBL10563612 | 0.78 | KCNH2 (0.33) | SMN1; SMN2KDM4EHPGD | |
| SCHEMBL5895323 | 0.77 | USP2 (0.47) | USP30USP2SMN1; SMN2ATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804665-A | NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-14 | — | — | US | disclosed |