Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP10 | P09238 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565385 | 0.84 | POLB (0.42) | CHRM2CHRM3CYP2D6ALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL10565807 | 0.81 | ITGB3 (0.37) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| SCHEMBL10568268 | 0.81 | USP30 (0.42) | USP2TSHRTHRBHPGD | |
| SCHEMBL10563612 | 0.78 | KCNH2 (0.33) | CHRM2CHRM3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10563363 | 0.72 | CHRM2 (0.33) | CHRM2CHRM3 | |
| SCHEMBL18711765 | 0.71 | USP2 (0.41) | USP2CYP2D6ALDH1A1CYP2C19TSHR | |
| SCHEMBL27256625 | 0.69 | CYP1A2 (0.43) | USP2CYP2D6ALDH1A1CYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL10563441 | 0.69 | CHRM2 (0.30) | CHRM2CHRM3ALDH1A1HPGD | |
| SCHEMBL18711770 | 0.68 | USP2 (0.39) | USP2CYP2D6ALDH1A1CYP2C19TSHR | |
| SCHEMBL18711764 | 0.67 | USP2 (0.38) | USP2CYP2D6ALDH1A1CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804665-A | NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-14 | — | — | US | disclosed |
| EP-0273659-A1 | Azaspiro compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |