Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572421 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10570315 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10568509 | 0.79 | MEN1 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10567008 | 0.78 | MEN1 (0.50) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10569154 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL10571171 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7803352 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10568854 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2TDP1 | |
| SCHEMBL10568967 | 0.73 | MEN1 (0.45) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10574092 | 0.73 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |