Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574092 | 0.90 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10567615 | 0.89 | MEN1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10569901 | 0.89 | MEN1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10576021 | 0.84 | KMT2A (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10568837 | 0.84 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10567233 | 0.84 | MEN1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10567008 | 0.82 | MEN1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10570273 | 0.81 | MEN1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10570567 | 0.80 | MEN1 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10568310 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |