Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181063 | 0.93 | MAPT (0.65) | MAPTCYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL10666615 | 0.85 | MAPT (0.55) | MAPTCYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL28384165 | 0.84 | MAPT (0.44) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL10666115 | 0.82 | MAPT (0.53) | MAPTCYP3A4MEN1KMT2ALMNA | |
| SCHEMBL1967437 | 0.81 | MAPT (0.65) | MAPTCYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL1923770 | 0.80 | MAPT (0.55) | MAPTCYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL10664398 | 0.80 | MAPT (0.60) | MAPTCYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL10664395 | 0.80 | MAPT (0.60) | MAPTCYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL2221110 | 0.80 | MAPT (0.77) | MAPTCYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL10915818 | 0.78 | MEN1 (0.51) | MAPTCYP3A4MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4380546-A | Azole compounds, their preparation, their use for crop treatment, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1983-04-19 | — | — | US | claimed |
| US-4822889-A | Triazolyl alcohols, their preparation and their use as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-18 | — | — | US | disclosed |
| US-4748250-A | Diastereoselective reduction of alpha-triazolylketones to betatriazolylcarbinols | BASF AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| US-4456608-A | Azole compounds, their preparation, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | disclosed |
| US-4380546-A | Azole compounds, their preparation, their use for crop treatment, and agents for this purpose | BASF AKTIENGESELLSCHAFT (DE) | 1983-04-19 | — | — | US | disclosed |