Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407564 | 0.86 | MAPT (0.55) | MAPTCYP3A4KMT2AHSP90AA1LMNA | |
| SCHEMBL12418531 | 0.86 | MAPT (0.58) | MAPTCYP3A4KMT2AHSP90AA1MEN1 | |
| SCHEMBL12415427 | 0.82 | MAPT (0.60) | MAPTCYP3A4KMT2AHSP90AA1MEN1 | |
| SCHEMBL3229143 | 0.82 | MAPT (0.39) | MAPTCYP3A4KMT2AHSP90AA1MEN1 | |
| SCHEMBL3121057 | 0.81 | MAPT (0.53) | MAPTCYP3A4KMT2AHSP90AA1MEN1 | |
| SCHEMBL10568398 | 0.80 | MAPT (0.62) | MAPTCYP3A4KMT2AMEN1LMNA | |
| SCHEMBL9748570 | 0.79 | MAPT (0.63) | MAPTCYP3A4KMT2AHSP90AA1MEN1 | |
| SCHEMBL10771521 | 0.78 | MAPT (0.55) | MAPTCYP3A4KMT2AHSP90AA1MEN1 | |
| SCHEMBL1967437 | 0.77 | MAPT (0.65) | MAPTCYP3A4KMT2AHSP90AA1MEN1 | |
| SCHEMBL1922846 | 0.77 | CYP3A4 (0.47) | MAPTCYP3A4KMT2AHSP90AA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166020-A1 | Imidazole and Triazole Compounds, Use Thereof and Agents Containing Said Compounds | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
| US-20110160056-A1 | Triazole compounds, the use thereof and preparations containing these compounds | BASF SE (DE) | 2011-06-30 | — | — | US | disclosed |
| EP-2334663-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2011-06-22 | — | — | EP | disclosed |
| EP-2328878-A1 | TRIAZOLE COMPOUNDS, THE USE THEREOF AND PREPARATIONS CONTAINING THESE COMPOUNDS | BASF SE (DE) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010029000-A1 | TRIAZOLE COMPOUNDS, THE USE THEREOF AND PREPARATIONS CONTAINING THESE COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010028974-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160056-A1 | Triazole compounds, the use thereof and preparations containing these compounds | CYP11B2, CYP3A43, CYP3A5 | MAPT 1402/4885CYP3A4 10/4885KMT2A 3231/4885 |
| US-20110166020-A1 | Imidazole and Triazole Compounds, Use Thereof and Agents Containing Said Compounds | COX4I1, NISCH, TPMT | MAPT 508/4885CYP3A4 14/4885KMT2A 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.