Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | FNTA | P49354 | 10/20 | 0.50 |
| ▸ | FNTB | P49356 | 10/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Closiramine SCHEMBL637355 | 0.87 | MEN1 (1.00) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102189 | 0.86 | MEN1 (0.58) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14288461 | 0.84 | MEN1 (0.56) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102072 | 0.84 | MEN1 (0.58) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102079 | 0.84 | MEN1 (0.56) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102196 | 0.80 | MEN1 (0.53) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14101997 | 0.77 | MEN1 (0.50) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL13611706 | 0.77 | FNTA (0.58) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102242 | 0.76 | MEN1 (0.49) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL1978262 | 0.75 | FNTA (0.60) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114748624-A | Composition for treating or preventing vasomotor symptoms | 田边三菱制药株式会社 | 2022-07-15 | — | — | CN | disclosed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-4831042-A | Tricyclic-substituted piperidine antihistamines | SCHERING CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4560688-A | NON-SEDATING; CARBAMOYL OR SULFONAMIDE DERIVATIVES | SCHERING CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| US-4454143-A | Tricyclic antihistamines | SCHERING CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4355036-A | Tricyclic-substituted piperidine antihistamines | SCHERING CORPORATION (US) | 1982-10-19 | — | — | US | disclosed |