Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 9/20 | 0.51 |
| ▸ | FNTB | P49356 | 9/20 | 0.51 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102189 | 0.85 | MEN1 (0.58) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102079 | 0.85 | MEN1 (0.56) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102072 | 0.85 | MEN1 (0.58) | MEN1KMT2AATMFNTAFNTB | |
| Closiramine SCHEMBL10568448 | 0.84 | MEN1 (0.75) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL13611706 | 0.78 | FNTA (0.58) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL1978262 | 0.76 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL14102196 | 0.75 | MEN1 (0.53) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL14102239 | 0.75 | MEN1 (0.51) | MEN1KMT2AATMFNTAFNTB | |
| SCHEMBL6176740 | 0.75 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL14289895 | 0.75 | FNTA (0.58) | FNTAFNTBSLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |