SCHEMBL10568479

SCHEMBL10568479

c1coc(Oc2ncco2)n1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28647909 0.92 LTA4H (0.33) LTA4H
SCHEMBL1680530 0.78
SCHEMBL29196122 0.78
SCHEMBL3123040 0.78
SCHEMBL446980 0.78
SCHEMBL22089484 0.78
SCHEMBL28356056 0.77
SCHEMBL3997755 0.76 ALDH1A1 (0.38) LTA4H
SCHEMBL3993876 0.75 ALDH1A1 (0.40) LTA4H
SCHEMBL3623632 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) 2025-09-25 US claimed
WO-2025021115-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2025-01-30 WO claimed
CN-114271270-B Composition for preventing and controlling sugarcane smut and preparation method thereof 广西壮族自治区农业科学院 2023-03-28 CN claimed
US-4863940-A N-acetonyl-substituted amides and phytopathogenic fungicidal use thereof ROHM AND HAAS (US) 1989-09-05 US claimed
US-12612383-B2 Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof SHANGHAI WENNAI THERAPEUTICS CO., LTD. (CN) 2026-04-28 US disclosed
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI WENNAI THERAPEUTICS CO LTD (CN) 2025-09-25 US disclosed
WO-2025021115-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2025-01-30 WO disclosed
CN-114271270-B Composition for preventing and controlling sugarcane smut and preparation method thereof 广西壮族自治区农业科学院 2023-03-28 CN disclosed
CN-115735644-A Navel orange pest and disease control method 重庆市彰榕农业发展有限公司 2023-03-07 CN disclosed
CN-114532334-B Azole ether and fine nail cream granules and preparation method thereof 山东汤普乐作物科学有限公司 2023-01-03 CN disclosed
CN-114532334-A Azole ether and fine nail cream granules and preparation method thereof 山东汤普乐作物科学有限公司 2022-05-27 CN disclosed
CN-114431063-A Planting method of fructus evodiae 广州白云山中一药业有限公司 2022-05-06 CN disclosed
CN-114271270-A Composition for preventing and controlling sugarcane smut and preparation method thereof 广西壮族自治区农业科学院 2022-04-05 CN disclosed
CN-105593714-A Long optical film, circularly polarizing plate provided with long optical film, and organic electroluminescent display device KONICA MINOLTA INC 2016-05-18 CN disclosed
US-20160003995-A1 OPTICAL FILM, CIRCULARLY POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-01-07 US disclosed
CN-100402510-C Oxazole derivatives and their use as insulin sensitizers HOFFMANN LA ROCHE (CH) 2008-07-16 CN disclosed
CN-1882524-A 4- ((phenoxyalkyl) thio) -phenoxyacetic acids and analogs JANSSEN PHARMACEUTICA NV (BE) 2006-12-20 CN disclosed
CN-1668606-A Oxazole derivatives and their use as insulin sensitizers HOFFMANN LA ROCHE (CH) 2005-09-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296922-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF SCN8A, SCN11A, TRPV1 LTA4H 1977/4885
US-12612383-B2 Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof SCN8A, SCN11A, TRPV1 LTA4H 3055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.