Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827441 | 0.83 | SOAT1 (0.46) | ALDH1A1SOAT1FFAR3LMNAHSD17B10 | |
| SCHEMBL5010949 | 0.78 | CES2 (0.42) | CES2CES1ALDH1A1SOAT1FFAR3 | |
| SCHEMBL2357526 | 0.74 | ALDH1A1 (0.39) | CES2CES1ALDH1A1SOAT1FFAR3 | |
| SCHEMBL13990789 | 0.74 | CES2 (0.42) | CES2CES1ALDH1A1FFAR3HDAC3 | |
| SCHEMBL215092 | 0.72 | SOAT1 (0.35) | CES2CES1ALDH1A1SOAT1HDAC3 | |
| SCHEMBL22092199 | 0.71 | HCAR2 (0.42) | ALDH1A1SOAT1FFAR3LMNAGAA | |
| SCHEMBL15531975 | 0.70 | ALDH1A1 (0.40) | ALDH1A1SOAT1MGAMGAASI | |
| SCHEMBL9839510 | 0.70 | SOAT1 (0.34) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL7546847 | 0.70 | SOAT1 (0.46) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL7174082 | 0.69 | ALDH1A1 (0.39) | CES2CES1ALDH1A1SOAT1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806549-A | INHIBITOR OF GASTRIC ACID SECRETION | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-21 | — | — | US | disclosed |