Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.42 |
| ▸ | HNF4A | P41235 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142632 | 0.93 | TYMS (0.50) | CA12CA7CA1CA4TYMS | |
| SCHEMBL1246295 | 0.91 | TYMS (0.49) | CA12CA7CA1CA4TYMS | |
| SCHEMBL1245664 | 0.89 | TYMS (0.50) | CA12CA7CA1CA4TYMS | |
| SCHEMBL17167769 | 0.87 | TYMS (0.45) | CA12CA7CA1CA4TYMS | |
| SCHEMBL168301 | 0.85 | TYMS (0.51) | CA12CA7CA1CA4TYMS | |
| SCHEMBL10514322 | 0.85 | POLB (0.51) | CA12CA7CA1CA4TYMS | |
| SCHEMBL29358248 | 0.84 | ALOX15 (0.57) | CA12CA7CA1CA4TYMS | |
| SCHEMBL169305 | 0.84 | ALOX15 (0.57) | CA12CA7CA1CA4TYMS | |
| SCHEMBL741462 | 0.84 | ALOX15 (0.57) | CA12CA7CA1CA4TYMS | |
| SCHEMBL29359977 | 0.84 | ALOX15 (0.57) | CA12CA7CA1CA4TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839217-A | FROM BIPHENYLTETRACARBOXYLIC ACID AND AROMATIC DIAMINE | UBE INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |