SCHEMBL169305

SCHEMBL169305

O=C1OC(=O)c2cc(-c3ccc4c(c3)C(=O)OC4=O)ccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
ALDH1A1 P00352 1/20 0.52
MEN1 O00255 1/20 0.45
APAF1 O14727 1/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
XBP1 P17861 1/20 0.45
PTBP1 P26599 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
GALK1 P51570 1/20 0.45
BLM P54132 1/20 0.45
SMAD3 P84022 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358248 1.00 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL741462 1.00 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL29423347 1.00 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL29359977 1.00 ALOX15 (0.57) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL308376 0.97 ALOX15 (0.55) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL29366467 0.97 ALOX15 (0.55) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL15641977 0.97 ALOX15 (0.55) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL17192488 0.97 ALOX15 (0.55) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL31097220 0.95 ALOX15 (0.52) ALOX15TDP1ALDH1A1MEN1APAF1
SCHEMBL21709537 0.95 ALOX15 (0.52) ALOX15TDP1ALDH1A1MEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4606840-A2 ISOCYANATE-FREE POLYURETHANE AND ISOCYANATE-FREE POLYURETHANE-CONTAINING POLYMERIC FILM PRODUCTION METHOD CHT Turkey Kimya Sanayi ve Ticaret A.S. (TR) 2025-08-27 EP claimed
EP-4455176-A1 WATER-SOLUBLE POLYMERIC STRUCTURE AND WATER-SOLUBLE POLYMERIC STRUCTURE PREPARATION METHOD CHT Turkey Kimya Sanayi ve Ticaret A.S. (TR) 2024-10-30 EP claimed
US-12129334-B2 Modified polyurethane carrier substrate KUROKI INDUSTRIAL CO., LTD. (TW) 2024-10-29 US claimed
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US claimed
EP-4428180-A1 ISOCYANATE-FREE POLYURETHANE AND ISOCYANATE-FREE POLYURETHANE-CONTAINING POLYMERIC FILM PRODUCTION METHOD CHT Turkey Kimya Sanayi ve Ticaret A.S. (TR) 2024-09-11 EP claimed
EP-4428168-A1 POLYURETHANE/OLIGOMERIC URETHANE SYNTHESIS METHOD BY RADIATION CHT Turkey Kimya Sanayi ve Ticaret A.S. (TR) 2024-09-11 EP claimed
US-20240026064-A1 MODIFIED POLYURETHANE CARRIER SUBSTRATE KUROKI INDUSTRIAL CO., LTD. (TW) 2024-01-25 US claimed
US-11535019-B2 Lignocellulosic composites and methods of making same COLLABORATIVE AGGREGATES, LLC (US) 2022-12-27 US claimed
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PSOMAGEN, INC. (US) 2022-08-23 US claimed
US-20210128498-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE MACROGEN INC. (KR) 2021-05-06 US claimed
US-20150146147-A1 Liquid Crystal Display Device and Method for Manufacturing the Same LG DISPLAY CO., LTD. (KR) 2015-05-28 US claimed
EP-2854260-A1 Slot plugging mass, slot seal and and method for producing a slot seal Siemens Aktiengesellschaft (DE) 2015-04-01 EP claimed
US-8901274-B2 Polyimide oligomers Lonza Group, Ltd. (CH) 2014-12-02 US claimed
WO-2014031139-A1 POLYIMIDE OLIGOMERS NOVOSET, LLC (US) 2014-02-27 WO claimed
US-20140058057-A1 Polyimide oligomers Arxada Switzerland AG (CH) 2014-02-27 US claimed
US-8426550-B2 Polyamic acid, polyimide, manufacturing method thereof, and polyimide film SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-04-23 US claimed
EP-0678563-B1 Active-energy-ray-curable coating composition MITSUBISHI CHEM CORP (JP) 1997-07-23 EP claimed
US-5565501-A ACRYLIC POLYMER; WEAR RESISTANCE MITSUBISHI CHEMICAL CORPORATION (JP) 1996-10-15 US claimed
EP-0678563-A1 Active-energy-ray-curable coating composition MITSUBISHI CHEMICAL CORPORATION (JP) 1995-10-25 EP claimed
US-5409965-A Abrasion resistant coating composition comprising a caboxylate-containing polyfunctional acrylate and silica sol MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-04-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PUF60, FTO, PARN ALOX15 1140/4885TDP1 1153/4885ALDH1A1 2713/4885
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PNMT, MAOA, HNMT ALOX15 3088/4885TDP1 761/4885ALDH1A1 988/4885
US-20210128498-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE MAOA, PNMT, HNMT ALOX15 1609/4885TDP1 1841/4885ALDH1A1 959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.