Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10568635 | 0.99 | POLB (0.51) | POLBHSD17B10DRD2HTR2AKDM4E | |
| SCHEMBL10573458 | 0.87 | POLB (0.51) | POLBHSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL10570788 | 0.85 | ABCB1 (0.45) | POLBHSD17B10KDM4EALDH1A1 | |
| SCHEMBL10568697 | 0.81 | DRD2 (0.52) | DRD2HTR2ADRD3DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL10572689 | 0.80 | POLB (0.55) | POLBHSD17B10ALDH1A1MEN1KMT2A | |
| Oxalic Acid SCHEMBL10573767 | 0.80 | KDM4E (0.48) | POLBHSD17B10KDM4EALDH1A1TDP1 | |
| SCHEMBL10652857 | 0.78 | POLB (0.51) | POLBHSD17B10KDM4EALDH1A1TDP1 | |
| SCHEMBL10570434 | 0.77 | POLB (0.50) | POLBHSD17B10ALDH1A1MEN1KMT2A | |
| Oxalic Acid SCHEMBL10580619 | 0.77 | KDM4E (0.49) | POLBHSD17B10DRD2HTR2AKDM4E | |
| SCHEMBL10570429 | 0.77 | POLB (0.49) | POLBHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845099-A | ANTIARRHYTHMIA AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | claimed |
| US-4845099-A | ANTIARRHYTHMIA AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |