Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568708 | 0.81 | POLB (0.52) | DRD2DRD3DRD4DRD1HTR2A | |
| Hydrochloric Acid SCHEMBL10568635 | 0.81 | POLB (0.51) | DRD2DRD3DRD4DRD1HTR2A | |
| SCHEMBL8648856 | 0.77 | ADRA1D (0.64) | DRD2DRD3DRD4HTR1AADRA1A | |
| SCHEMBL11277272 | 0.75 | HTR2A (0.67) | DRD2DRD3DRD4DRD1HTR2A | |
| SCHEMBL11808685 | 0.75 | HTR2A (0.67) | DRD2DRD3DRD4DRD1HTR2A | |
| SCHEMBL9121058 | 0.72 | HTR2A (0.59) | DRD2DRD3DRD4DRD1HTR2A | |
| SCHEMBL9119424 | 0.69 | HTR1A (0.59) | DRD2DRD3DRD4DRD1HTR2A | |
| Dimetholizine SCHEMBL2110772 | 0.69 | DRD2 (0.76) | DRD2DRD3HTR2AHTR7HTR1A | |
| SCHEMBL11827962 | 0.69 | DRD3 (0.70) | DRD2DRD3DRD1HRH3HTR2A | |
| SCHEMBL11274506 | 0.69 | SLC6A2 (0.72) | DRD2DRD3DRD4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845099-A | ANTIARRHYTHMIA AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |