Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753834 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL9825008 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL10889600 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL11405713 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL31706386 | 0.79 | ADAM17 (0.69) | ALDH1A1MEN1KMT2AMAPTGAA | |
| Bromide SCHEMBL11272474 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL9350619 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTGAASMN1; SMN2GFER | |
| SCHEMBL11751976 | 0.74 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL9354256 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPTGAATSHRHSP90AA1 | |
| SCHEMBL22898691 | 0.73 | KMT2A (0.63) | ALDH1A1HSD17B10MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0173284-A1 | Substituted 1-phenyl-3-methyl-pyrrolidindiones, their manufacture and use as fungicides | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |
| US-4009278-A | Antimicrobial composition and method containing N-(3,5-dihalophenyl)-imide compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |