Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570669 | 0.88 | MEN1 (0.54) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10572098 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10565605 | 0.86 | TSHR (0.52) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10566913 | 0.84 | MEN1 (0.53) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10570577 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10567596 | 0.81 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10573727 | 0.78 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL10571542 | 0.78 | MEN1 (0.53) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10569901 | 0.77 | MEN1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10568989 | 0.77 | MEN1 (0.43) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0173284-A1 | Substituted 1-phenyl-3-methyl-pyrrolidindiones, their manufacture and use as fungicides | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |