Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571229 | 0.82 | GLA (0.49) | GLAKMT2AFBP1ALDH1A1CYP2C19 | |
| SCHEMBL10567359 | 0.81 | KMT2A (0.49) | KMT2AFBP1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4185645 | 0.77 | KMT2A (0.51) | KMT2AFBP1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10642276 | 0.76 | FBP1 (0.51) | KMT2AFBP1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL17277540 | 0.74 | KMT2A (0.49) | KMT2AFBP1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8257058 | 0.74 | KMT2A (0.51) | KMT2AFBP1ALDH1A1HCRTR2 | |
| SCHEMBL5181113 | 0.73 | KMT2A (0.55) | KMT2AFBP1ALDH1A1HCRTR2CNR2 | |
| SCHEMBL6098155 | 0.72 | KMT2A (0.58) | KMT2AFBP1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL27856386 | 0.71 | KMT2A (0.45) | KMT2AFBP1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10583477 | 0.70 | ALDH1A1 (0.50) | GLAKMT2AFBP1ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810706-A | ANTIHISTAMINES | RECHERCHE SYNTEX (FR) | 1989-03-07 | — | — | US | disclosed |
| EP-0227077-A1 | Piperazine derivatives of theophylline and theobromine | LABORATOIRES SYNTEX S.A. (FR) | 1987-07-01 | — | — | EP | disclosed |