Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566464 | 0.87 | RAB9A (0.56) | ALDH1A1SMN1; SMN2MAOBRAB9AMAPK1 | |
| SCHEMBL10824903 | 0.85 | NPC1 (0.62) | ALDH1A1GAAKLK7SMN1; SMN2MAOB | |
| SCHEMBL10568683 | 0.85 | RAB9A (0.53) | ALDH1A1SMN1; SMN2MAOBRAB9AMAPK1 | |
| SCHEMBL3732393 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAAKLK7SMN1; SMN2RAB9A | |
| SCHEMBL11684699 | 0.82 | ALDH1A1 (0.74) | ALDH1A1GAAKLK7SMN1; SMN2RAB9A | |
| SCHEMBL1171464 | 0.82 | ALDH1A1 (0.74) | ALDH1A1GAAKLK7SMN1; SMN2RAB9A | |
| SCHEMBL23154876 | 0.79 | ALDH1A1 (0.59) | ALDH1A1GAAKLK7SMN1; SMN2MAOA | |
| SCHEMBL6207604 | 0.79 | RAB9A (0.59) | ALDH1A1SMN1; SMN2MAOAMAOBRAB9A | |
| SCHEMBL6210030 | 0.79 | RAB9A (0.59) | ALDH1A1SMN1; SMN2MAOAMAOBRAB9A | |
| SCHEMBL11703006 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAKLK7SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4834905-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |
| US-4627933-A | ESTERS, ETHERS, NITRICES, HALIDES, OR HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-12-09 | — | — | US | disclosed |