SCHEMBL10569752

SCHEMBL10569752

C=CCSN1CNCNC1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX5 P09917 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27674640 0.78
SCHEMBL10511159 0.70
SCHEMBL25525342 0.69
SCHEMBL8608609 0.64
SCHEMBL11045028 0.54
SCHEMBL18051607 0.53
Diallyl Sulfide SCHEMBL4346718 0.51
Diallyldisulfide SCHEMBL18687005 0.51 TRPA1 (1.00) TRPA1ALDH1A1CYP3A4HPGDALOX15
Diallyl Sulfide SCHEMBL14764035 0.51 ALOX5 (1.00) TRPA1ALDH1A1CYP3A4HPGDALOX15
Diallyldisulfide SCHEMBL93944 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4846881-A AMINO OR THIO DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1989-07-11 US disclosed
EP-0284901-A1 3,4,6-Trisubstituted 1,2,4-triazin-5(4H)-ones BAYER AG (DE) 1988-10-05 EP disclosed