Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572027 | 0.96 | ACHE (0.50) | ACHEBCHEMEN1KMT2ATDP1 | |
| SCHEMBL10573809 | 0.90 | ACHE (0.46) | ACHEBCHEMEN1KMT2ATDP1 | |
| SCHEMBL10573396 | 0.85 | ACHE (0.55) | ACHEBCHE | |
| SCHEMBL10572159 | 0.84 | ACHE (0.49) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL10572348 | 0.82 | ACHE (0.47) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL10572075 | 0.78 | ACHE (0.51) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL10572246 | 0.76 | ACHE (0.68) | ACHEBCHEKMT2A | |
| SCHEMBL10481927 | 0.74 | ACHE (0.47) | ACHEBCHE | |
| SCHEMBL10612178 | 0.74 | ACHE (0.47) | ACHEBCHE | |
| SCHEMBL7380712 | 0.74 | ACHE (0.56) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816464-A | ANTIINFLAMMATORY AGENTS, ENZYME TISSUE DESTRUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-28 | — | — | US | claimed |
| US-4816464-A | ANTIINFLAMMATORY AGENTS, ENZYME TISSUE DESTRUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |