Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384764 | 0.87 | ACHE (0.54) | ACHESOS1BCHECYP1A2CYP3A4 | |
| SCHEMBL7383945 | 0.85 | ACHE (0.52) | ACHESOS1BCHECYP1A2CYP3A4 | |
| Water SCHEMBL7385383 | 0.84 | ACHE (0.51) | ACHESOS1BCHECYP1A2CYP3A4 | |
| Water SCHEMBL7385385 | 0.84 | ACHE (0.51) | ACHESOS1BCHECYP1A2CYP3A4 | |
| SCHEMBL7375848 | 0.81 | ACHE (0.46) | ACHEALDH1A1 | |
| SCHEMBL7388062 | 0.80 | SMYD3 (0.52) | ACHEKDM4EALDH1A1BCHE | |
| SCHEMBL10573396 | 0.79 | ACHE (0.55) | ACHESOS1BCHECYP1A2CYP3A4 | |
| SCHEMBL7386411 | 0.79 | ACHE (0.57) | ACHESOS1BCHECYP1A2CYP3A4 | |
| SCHEMBL7377027 | 0.77 | ACHE (0.55) | ACHESOS1BCHECYP1A2CYP3A4 | |
| SCHEMBL28874700 | 0.74 | MAPT (0.59) | ACHEKDM4EALDH1A1BCHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851536-A | ANTIFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-25 | — | — | US | claimed |
| US-4970316-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-11-13 | — | — | US | disclosed |
| US-4851536-A | ANTIFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |