Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400765 | 0.91 | CHRM1 (0.42) | ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL9400768 | 0.91 | CHRM1 (0.42) | ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL3317652 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10RAB9ACYP2C19POLB | |
| SCHEMBL7330432 | 0.80 | CHRM1 (0.42) | ALDH1A1 | |
| SCHEMBL9698264 | 0.77 | ALDH1A1 (0.44) | ALDH1A1RAB9APOLBHTTATM | |
| SCHEMBL9696817 | 0.74 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL3319442 | 0.73 | CHRM2 (0.42) | ALDH1A1HSD17B10NPSR1L3MBTL1 | |
| SCHEMBL3314224 | 0.71 | CHRM1 (0.40) | — | |
| SCHEMBL10569876 | 0.70 | CHRM1 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10567916 | 0.69 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870081-A | DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1989-09-26 | — | — | US | disclosed |
| EP-0257741-A2 | Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-03-02 | — | — | EP | disclosed |