⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572777 | 0.96 | — | — | |
| SCHEMBL10569345 | 0.89 | — | — | |
| SCHEMBL10571302 | 0.88 | DRD2 (0.61) | — | |
| SCHEMBL10665459 | 0.87 | HRH1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL10570746 | 0.85 | DRD2 (0.58) | — | |
| SCHEMBL10571945 | 0.84 | DRD2 (0.64) | — | |
| SCHEMBL10572411 | 0.83 | DRD2 (0.56) | — | |
| SCHEMBL10568168 | 0.83 | DRD2 (0.56) | — | |
| SCHEMBL10570860 | 0.83 | DRD2 (0.61) | — | |
| SCHEMBL10571216 | 0.83 | DRD2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |