Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570344 | 0.87 | DRD2 (0.63) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10570746 | 0.87 | DRD2 (0.58) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL10572777 | 0.87 | — | — | |
| SCHEMBL11068538 | 0.85 | CHRM2 (0.57) | DRD2DRD3DRD4CHRM2CHRM4 | |
| SCHEMBL10572411 | 0.85 | DRD2 (0.56) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL10570860 | 0.84 | DRD2 (0.61) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL10571216 | 0.84 | DRD2 (0.61) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL11068257 | 0.84 | ADRB2 (0.59) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL10660200 | 0.84 | HTR7 (0.48) | DRD2DRD3DRD4ADRB2CHRM2 | |
| SCHEMBL10570239 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55162774-A | — | — | None | — | — | JP | disclosed |
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| JP-S55162774-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1980-12-18 | — | — | JP | disclosed |