Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577830 | 0.93 | REN (0.52) | REN | |
| SCHEMBL10572207 | 0.93 | REN (0.48) | REN | |
| SCHEMBL10571933 | 0.92 | REN (0.49) | REN | |
| SCHEMBL10570895 | 0.91 | MMP2 (0.49) | REN | |
| SCHEMBL10571479 | 0.91 | REN (0.49) | REN | |
| SCHEMBL10825063 | 0.90 | REN (0.48) | REN | |
| SCHEMBL10573427 | 0.89 | REN (0.47) | REN | |
| SCHEMBL10573424 | 0.89 | REN (0.47) | REN | |
| SCHEMBL10721178 | 0.89 | REN (0.60) | REN | |
| SCHEMBL10721187 | 0.89 | REN (0.60) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4841067-A | RENIN INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0190891-A2 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1986-08-13 | — | — | EP | disclosed |