Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297582 | 0.93 | MAPT (0.41) | KDM4EMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL7297497 | 0.91 | MAOA (0.33) | KDM4EMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL7292065 | 0.88 | HTT (0.37) | KDM4EMAPTSMN1; SMN2HTTGAA | |
| SCHEMBL7297343 | 0.86 | CNR2 (0.34) | KDM4ESMN1; SMN2GAAPOLBPDE4A | |
| SCHEMBL7286803 | 0.85 | VHL (0.42) | KDM4EMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL7286064 | 0.84 | MAPT (0.39) | KDM4EMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL10558711 | 0.82 | MAPT (0.43) | KDM4EMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL9864982 | 0.82 | KDM4E (0.40) | KDM4EMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL7379926 | 0.82 | MAPT (0.33) | KDM4EMAPTHTTLMNAGAA | |
| SCHEMBL7288749 | 0.81 | GRM5 (0.36) | MAPTSMN1; SMN2HTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849421-A | SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-07-18 | — | — | US | disclosed |