Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558711 | 0.89 | MAPT (0.43) | KDM4ESMN1; SMN2MAPTNPSR1LMNA | |
| SCHEMBL10560169 | 0.88 | KDM4E (0.37) | KDM4ESMN1; SMN2MAP3K7TAB1MAOB | |
| SCHEMBL10564407 | 0.87 | APP (0.43) | KDM4ESMN1; SMN2MAPTNPSR1LMNA | |
| SCHEMBL9866556 | 0.86 | PRKCZ (0.38) | KDM4ESMN1; SMN2MAPTNPSR1LMNA | |
| SCHEMBL9601585 | 0.85 | MIF (0.36) | KDM4ESMN1; SMN2MAPTMAP3K7TAB1 | |
| SCHEMBL7297497 | 0.83 | MAOA (0.33) | KDM4ESMN1; SMN2MAPTNPSR1LMNA | |
| SCHEMBL10570570 | 0.82 | KDM4E (0.37) | KDM4ESMN1; SMN2MAPTNPSR1LMNA | |
| SCHEMBL10560355 | 0.81 | HTT (0.38) | KDM4ESMN1; SMN2MAPTHTTRAB9A | |
| SCHEMBL10556208 | 0.81 | MAPT (0.40) | KDM4ESMN1; SMN2MAPTNPSR1LMNA | |
| SCHEMBL10560262 | 0.80 | APP (0.42) | KDM4ESMN1; SMN2MAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |