Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.43 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571839 | 0.86 | MEN1 (0.41) | ACHEBCHECHRM1EPHX2KMT2A | |
| SCHEMBL10572159 | 0.81 | ACHE (0.49) | ACHEBCHEKMT2AMEN1 | |
| SCHEMBL10572348 | 0.80 | ACHE (0.47) | ACHEBCHECHRM1EPHX2KMT2A | |
| SCHEMBL10572075 | 0.78 | ACHE (0.51) | ACHEBCHECHRM1EPHX2KMT2A | |
| SCHEMBL10575185 | 0.77 | ACHE (0.49) | ACHEBCHECHRM1EPHX2MAPT | |
| SCHEMBL10611520 | 0.72 | ACHE (0.44) | ACHEBCHECHRM1EPHX2MAPT | |
| SCHEMBL10481965 | 0.71 | MAPT (0.53) | ACHEBCHECHRM1EPHX2KMT2A | |
| SCHEMBL4266767 | 0.70 | ACHE (0.74) | ACHEBCHECHRM1EPHX2MAPT | |
| SCHEMBL10573809 | 0.70 | ACHE (0.46) | ACHEBCHEKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9659901 | 0.70 | MAPT (0.40) | KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816464-A | ANTIINFLAMMATORY AGENTS, ENZYME TISSUE DESTRUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-28 | — | — | US | claimed |
| US-4816464-A | ANTIINFLAMMATORY AGENTS, ENZYME TISSUE DESTRUCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |