Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657939 | 0.83 | SMN1; SMN2 (0.32) | ACHESMN1; SMN2CA1CA9 | |
| SCHEMBL8930024 | 0.81 | ACHE (0.30) | ACHE | |
| SCHEMBL4508473 | 0.81 | POLB (0.32) | ACHE | |
| SCHEMBL2412750 | 0.78 | ACHE (0.53) | ACHE | |
| SCHEMBL5881177 | 0.75 | KDM4E (0.44) | ACHEKDM4EALDH1A1LMNAGAA | |
| SCHEMBL9886141 | 0.70 | SLC6A3 (0.34) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28178052 | 0.70 | SLC6A3 (0.38) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL21295443 | 0.70 | — | — | |
| SCHEMBL11146267 | 0.70 | CA1 (0.30) | CA1CA9 | |
| SCHEMBL27455242 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924175-A | Preparation method of 3, 5-dimethyl-1H-pyrazole-4-propanol | 甘肃汇健药业有限公司 | 2024-04-26 | — | — | CN | claimed |
| US-20240239751-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | BRIDGEBIO GENE THERAPY RESEARCH, INC. | 2024-07-18 | — | — | US | disclosed |
| US-20240239751-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | BRIDGEBIO GENE THERAPY RESEARCH, INC. | 2024-07-18 | — | — | US | disclosed |
| CN-117924175-A | Preparation method of 3, 5-dimethyl-1H-pyrazole-4-propanol | 甘肃汇健药业有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-11078162-B2 | Processes for preparing AG-10, its intermediates, and salts thereof | Eidos Therapeutics, Inc. (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200247756-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | Ferro Therapeutics, Inc. | 2020-08-06 | — | — | US | disclosed |
| US-4843080-A | VASODILATION; CARDIOVASCULAR ACTIVITY; CHEMICAL INTERMEDIATES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-06-27 | — | — | US | disclosed |
| EP-0202774-A2 | 1,12b-Disubstituted octahydroindolo [2,3-a]-Quinolizine derivatives | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078162-B2 | Processes for preparing AG-10, its intermediates, and salts thereof | UGT1A10, SAMM50, AGL | ACHE 417/4885KDM4E 2765/4885ALDH1A1 895/4885 |
| US-20200247756-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | UGT1A10, SAMM50, AGL | ACHE 417/4885KDM4E 2765/4885ALDH1A1 895/4885 |
| US-20240239751-A1 | PROCESSES FOR PREPARING AG-10, ITS INTERMEDIATES, AND SALTS THEREOF | UGT1A10, SAMM50, AGL | ACHE 417/4885KDM4E 2765/4885ALDH1A1 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.