Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574468 | 1.00 | NPC1 (0.46) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL7993671 | 0.81 | GAA (0.41) | NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL7993674 | 0.81 | GAA (0.41) | NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL7995353 | 0.81 | ALDH1A1 (0.36) | NPC1RAB9AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL7995355 | 0.81 | ALDH1A1 (0.36) | NPC1RAB9AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL11860696 | 0.78 | GAA (0.63) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL7993571 | 0.74 | CHRNB2 (0.54) | RAB9AL3MBTL1GAASMN1; SMN2MEN1 | |
| SCHEMBL7993578 | 0.74 | CHRNB2 (0.54) | RAB9AL3MBTL1GAASMN1; SMN2MEN1 | |
| SCHEMBL11373206 | 0.73 | GAA (0.43) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL11373210 | 0.73 | GAA (0.43) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | claimed |
| US-4880933-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0277317-A1 | Nitro derivatives of 2-iminoimidazolidines and 2-iminotetrahydropyrimidines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-10 | — | — | EP | disclosed |