Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | ACR | P10323 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412131 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL10577524 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL10576380 | 1.00 | ADRB2 (0.55) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL8917247 | 0.96 | ADRB2 (0.58) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL8915082 | 0.96 | ADRB2 (0.58) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL9879287 | 0.93 | ADRB2 (0.48) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL9879291 | 0.93 | ADRB2 (0.48) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL8940379 | 0.93 | ADRB2 (0.48) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL8940376 | 0.93 | ADRB2 (0.48) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 | |
| SCHEMBL8915031 | 0.89 | MAPT (0.62) | ADRB2ADRB1ADRB3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864033-A | ATTACHED TO POLYSILOXANE BACKBONE, FOR CHROMATOGRAPHIC SEPARATION OF POLYCYCLIC AROMATIC HYDROCARBONS | BRIGHAM YOUNG UNIVERSITY (US) | 1989-09-05 | — | — | US | disclosed |