Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879287 | 1.00 | ADRB2 (0.48) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL8940379 | 1.00 | ADRB2 (0.48) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL9879291 | 1.00 | ADRB2 (0.48) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL10577524 | 0.93 | ADRB2 (0.55) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL10576384 | 0.93 | ADRB2 (0.55) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL10576380 | 0.93 | ADRB2 (0.55) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL9412131 | 0.93 | ADRB2 (0.55) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL9878246 | 0.90 | PPARD (0.47) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL9878245 | 0.90 | PPARD (0.47) | ADRB2ADRB1ADRB3CYP2D6MAPT | |
| SCHEMBL12225731 | 0.90 | PPARD (0.47) | ADRB2ADRB1ADRB3CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563230-A | POLYETHERSILOXANES | NATIONAL SCIENCE COUNCIL (TW) | 1996-10-08 | — | — | US | disclosed |