Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577394 | 0.90 | KDM4E (0.42) | SCN10AKDM4ELMNAHSD17B10ALDH1A1 | |
| SCHEMBL10578941 | 0.84 | MAPT (0.51) | SCN10AKDM4EHSD17B10ALDH1A1KCNH2 | |
| SCHEMBL10575570 | 0.82 | PLAU (0.42) | SCN10AHSD17B10ALDH1A1KCNH2 | |
| SCHEMBL10579210 | 0.82 | SCN10A (0.38) | SCN10AHSD17B10KCNH2 | |
| SCHEMBL10694817 | 0.82 | SCN10A (0.40) | SCN10AHSD17B10KCNH2 | |
| SCHEMBL10577964 | 0.81 | HPGD (0.47) | SCN10AHSD17B10ALDH1A1CYP1A2KCNH2 | |
| SCHEMBL12404648 | 0.80 | SCN10A (0.54) | SCN10AKDM4ELMNAHSD17B10ALDH1A1 | |
| SCHEMBL10579387 | 0.80 | KDM4E (0.48) | SCN10AKDM4ELMNAALDH1A1 | |
| SCHEMBL10579145 | 0.79 | CACNA1H (0.39) | SCN10ALMNAALDH1A1KCNH2 | |
| SCHEMBL10578090 | 0.79 | TRPV1 (0.47) | SCN10AKDM4ELMNAALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |