Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 13/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694806 | 0.90 | SCN10A (0.30) | SCN10A | |
| SCHEMBL10578941 | 0.86 | MAPT (0.51) | SCN10AKCNH2GAAMAPTHSD17B10 | |
| SCHEMBL10575570 | 0.85 | PLAU (0.42) | SCN10AKCNH2GAAMAPTHSD17B10 | |
| SCHEMBL10579210 | 0.85 | SCN10A (0.38) | SCN10AKCNH2GCGRCSNK1A1CSNK1D | |
| SCHEMBL10576865 | 0.83 | HDAC6 (0.43) | KCNH2HDAC6GAAMAPTHSD17B10 | |
| SCHEMBL10577338 | 0.83 | DGAT1 (0.57) | KCNH2HDAC6MAPTDGAT1 | |
| SCHEMBL10573861 | 0.83 | SCN10A (0.38) | SCN10AKCNH2CSNK1A1CSNK1DGSK3B | |
| SCHEMBL10577402 | 0.82 | SCN10A (0.46) | SCN10AKCNH2HSD17B10 | |
| SCHEMBL10577964 | 0.82 | HPGD (0.47) | SCN10AKCNH2GCGRCSNK1A1CSNK1D | |
| SCHEMBL10579387 | 0.81 | KDM4E (0.48) | SCN10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |