Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20281140 | 0.80 | SERPINA6 (0.59) | CYP3A4MEN1LMNAMAPK1KMT2A | |
| SCHEMBL16742396 | 0.78 | SHBG (0.67) | CYP3A4MEN1LMNAALOX15MAPK1 | |
| SCHEMBL16739258 | 0.78 | SHBG (0.67) | CYP3A4MEN1LMNAALOX15MAPK1 | |
| SCHEMBL6818142 | 0.78 | SHBG (0.67) | CYP3A4MEN1LMNAALOX15MAPK1 | |
| SCHEMBL10577802 | 0.78 | SHBG (0.59) | CYP3A4LMNAMAPK1CYP19A1ESR1 | |
| SCHEMBL20408880 | 0.78 | SHBG (0.59) | CYP3A4LMNAMAPK1CYP19A1ESR1 | |
| SCHEMBL2930366 | 0.76 | MAPT (0.71) | CYP3A4MEN1LMNAALOX15MAPK1 | |
| SCHEMBL17302789 | 0.76 | MAPT (0.71) | CYP3A4MEN1LMNAALOX15MAPK1 | |
| SCHEMBL13415930 | 0.76 | CYP17A1 (0.52) | CYP3A4MEN1LMNAALOX15MAPK1 | |
| SCHEMBL28600625 | 0.76 | SHBG (0.44) | CYP3A4MEN1LMNAALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874898-A | ANTIANDROGENS | SHIONOGI AND CO., LTD. PATENT DEPARTMENT (JP) | 1989-10-17 | — | — | US | disclosed |