SCHEMBL2930366

SCHEMBL2930366

CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.71
▸ LMNA P02545 2/20 0.71
▸ SERPINA6 P08185 2/20 0.71
▸ ALDH1A1 P00352 2/20 0.68
▸ SLC22A1 O15245 1/20 0.68
▸ SHBG P04278 1/20 0.68
▸ THRB P10828 1/20 0.68
▸ MCL1 Q07820 1/20 0.64
▸ CYP1A2 P05177 1/20 0.64
▸ HIF1A Q16665 1/20 0.64
▸ HSD17B10 Q99714 1/20 0.64
▸ CYP19A1 P11511 2/20 0.56
▸ PGR P06401 2/20 0.56
▸ MEN1 O00255 2/20 0.56
▸ CYP3A4 P08684 2/20 0.56
▸ MAPK1 P28482 2/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ NR3C1 P04150 1/20 0.56
▸ CHRM2 P08172 1/20 0.56
▸ ADORA3 P0DMS8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17302789 1.00 MAPT (0.71) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL13177160 1.00 MAPT (0.71) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL13804528 1.00 MAPT (0.71) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL3458086 0.91 MAPT (0.71) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL24103254 0.90 MAPT (0.69) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL9473555 0.90 MAPT (0.69) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL6445859 0.90 MAPT (0.69) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL24103304 0.90 MAPT (0.69) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL21067996 0.89 MAPT (0.84) MAPTLMNASERPINA6ALDH1A1SLC22A1
SCHEMBL343128 0.88 MAPT (0.79) MAPTLMNASERPINA6ALDH1A1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-216295310-U A filtrating collection device for production of dehydrogenation nandrolone acetate 湖北三晶生物科技股份有限公司 2022-04-15 — — CN claimed
CN-107353318-A The preparation method of 6 dehydrogenation nandrolone acetates 湖北共同生物科技有限公司 2017-11-17 — — CN claimed
CN-107188916-A A kind of preparation method of 6 dehydrogenation nandrolone acetate 湖北工业大学 2017-09-22 — — CN claimed
US-20250281509-A1 SEQUENTIAL HORMONE THERAPY TO IMPROVE SURVIVAL AND ENHANCE RESPONSE TO IMMUNE THERAPY IN MEN WITH PROSTATE CANCER THE JOHNS HOPKINS UNIVERSTY 2025-09-11 — — US disclosed
US-11912737-B2 19-nor neuroactive steroids and methods of use thereof Sage Therpeutics, Inc. (US) 2024-02-27 — — US disclosed
US-11912737-B2 19-nor neuroactive steroids and methods of use thereof Sage Therpeutics, Inc. (US) 2024-02-27 — — US disclosed
EP-4144746-A1 NEUROACTIVE STEROIDS, COMPOSITIONS AND USES THEREOF Sage Therapeutics, Inc. (US) 2023-03-08 — — EP disclosed
CN-216295310-U A filtrating collection device for production of dehydrogenation nandrolone acetate 湖北三晶生物科技股份有限公司 2022-04-15 — — CN disclosed
CN-216295310-U A filtrating collection device for production of dehydrogenation nandrolone acetate 湖北三晶生物科技股份有限公司 2022-04-15 — — CN disclosed
CN-216295310-U A filtrating collection device for production of dehydrogenation nandrolone acetate 湖北三晶生物科技股份有限公司 2022-04-15 — — CN disclosed
US-11241446-B2 19-nor C3, 3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof SAGE THERAPEUTICS, INC. (US) 2022-02-08 — — US disclosed
US-4048195-A Process of synthesizing substituted indanones HOFFMANN-LA ROCHE INC. (US) 1977-09-13 — — US disclosed
US-4044004-A Total steroid synthesis employing substituted isoxazole derivatives HOFFMANN-LA ROCHE INC. (US) 1977-08-23 — — US disclosed
US-4004005-A NON-PYROGENIC AKZONA INCORPORATED (US) 1977-01-18 — — US disclosed
US-3985733-A Stereospecific total steroidal synthesis via substituted C/D-trans indanones HOFFMANN-LA ROCHE INC. (US) 1976-10-12 — — US disclosed
US-3985771-A Total steroid synthesis employing substituted isoxazole derivatives HOFFMANN-LA ROCHE INC. (US) 1976-10-12 — — US disclosed
US-3984473-A Stereospecific total steroidal synthesis via substituted C/D-trans indanones HOFFMANN-LA ROCHE INC. (US) 1976-10-05 — — US disclosed
US-3984428-A Isoxazolyl-substituted perhydrobenzindenes HOFFMANN-LA ROCHE INC. (US) 1976-10-05 — — US disclosed
US-3965117-A Stereospecific total steroidal synthesis via substituted c/d-trans indanones HOFFMANN-LA ROCHE INC. (US) 1976-06-22 — — US disclosed
US-3950389-A Stereospecific total steroidal synthesis via substituted C/D-trans indanones HOFFMANN-LA ROCHE INC. (US) 1976-04-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912737-B2 19-nor neuroactive steroids and methods of use thereof NR3C2, HSD3B1, HSD3B2 MAPT 1029/4885LMNA 2913/4885SERPINA6 407/4885
US-11241446-B2 19-nor C3, 3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof NR3C2, NR3C1, CYP11B1 MAPT 1772/4885LMNA 2657/4885SERPINA6 1023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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